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Cellular identity crisis: Antiandrogen resistance by lineage plasticity
A recent publication in Science demonstrates the ability of prostate cancer cells to switch lineages from one that is dependent on androgen signaling to a cell type that is not. Known as lineage plasticity, this phenomenon is driven by the transcription factor SOX2 in RB1 and TP53-deficient prostate...
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| 出版年: | Cancer Biol Ther |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5710664/ https://ncbi.nlm.nih.gov/pubmed/28475401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1323599 |
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