Loss of OATP1B3 function causes Rotor syndrome: Implications for potential use of inhibitors in cancer

There has been increasing recognition that organic anion transporter proteins (OATPs) play an important role in the biology of various cancers. De novo expression of OATPs has been identified in breast, colon, pancreatic, gastric and prostate cancer cells, among others.(1) In patients with prostate...

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Bibliographic Details
Main Authors: Pratt, Elias, Sissung, Tristan M., Figg, William D.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Journal Club
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542226/
https://ncbi.nlm.nih.gov/pubmed/22954695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22010
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