Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex

IMPORTANCE: Abnormal accumulation of tau and amyloid-β (Aβ) proteins in the human brain are 2 pathologic hallmarks of Alzheimer disease (AD). Because pathologic processes begin decades before the onset of the clinical manifestations, the study of the cortical distribution of early-stage pathologic a...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Sepulcre, Jorge, Grothe, Michel J., Sabuncu, Mert, Chhatwal, Jasmeer, Schultz, Aaron P., Hanseeuw, Bernard, El Fakhri, Georges, Sperling, Reisa, Johnson, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710537/
https://ncbi.nlm.nih.gov/pubmed/28558094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.0263
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