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Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase

Disruption of the balanced modulation of reversible tyrosine phosphorylation has been implicated in the etiology of various human cancers, including breast cancer. Protein Tyrosine Phosphatase N23 (PTPN23) resides in chromosomal region 3p21.3, which is hemizygously or homozygously lost in some breas...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Zhang, Siwei, Fan, Gaofeng, Hao, Yuan, Hammell, Molly, Wilkinson, John Erby, Tonks, Nicholas K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710140/
https://ncbi.nlm.nih.gov/pubmed/29066500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.304261.117
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