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HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer

Ovarian cancer cells disseminate readily within the peritoneal cavity, which promotes metastasis, and are often resistant to chemotherapy. Ovarian cancer patients tend to present with advanced disease, which also limits treatment options; consequently, new therapies are required. The oncoprotein tyr...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Fan, Gaofeng, Zhang, Siwei, Gao, Yan, Greer, Peter A., Tonks, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949327/
https://ncbi.nlm.nih.gov/pubmed/27401557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284166.116
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