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FER mediated HGF-independent regulation of HGFR/MET activates RAC1-PAK1 pathway to potentiate metastasis in ovarian cancer

Uncontrolled metastasis significantly contributes to high lethality of patients suffering from ovarian cancer. To date, the detailed molecular mechanisms which account for ovarian tumor cell spreading and metastasis remain largely unknown. In a recent study, we have demonstrated that aberrantly high...

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Detalhes bibliográficos
Publicado no:Small GTPases
Autor principal: Fan, Gaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549699/
https://ncbi.nlm.nih.gov/pubmed/29099290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1379931
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