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Protein-tyrosine Phosphatase 1B Antagonized Signaling by Insulin-like Growth Factor-1 Receptor and Kinase BRK/PTK6 in Ovarian Cancer Cells

Ovarian cancer, which is the leading cause of death from gynecological malignancies, is a heterogeneous disease known to be associated with disruption of multiple signaling pathways. Nevertheless, little is known regarding the role of protein phosphatases in the signaling events that underlie the di...

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Detalhes bibliográficos
Main Authors: Fan, Gaofeng, Lin, Guang, Lucito, Robert, Tonks, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750187/
https://ncbi.nlm.nih.gov/pubmed/23814047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482737
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