Cerebrovascular pathology in Down syndrome and Alzheimer disease

People with Down syndrome (DS) are at high risk for developing Alzheimer disease (AD) with age. Typically, by age 40 years, most people with DS have sufficient neuropathology for an AD diagnosis. Interestingly, atherosclerosis and hypertension are atypical in DS with age, suggesting the lack of thes...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Head, Elizabeth, Phelan, Michael J., Doran, Eric, Kim, Ronald C., Poon, Wayne W., Schmitt, Frederick A., Lott, Ira T.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709935/
https://ncbi.nlm.nih.gov/pubmed/29195510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0499-4
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