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Cerebrovascular pathology in Down syndrome and Alzheimer disease

People with Down syndrome (DS) are at high risk for developing Alzheimer disease (AD) with age. Typically, by age 40 years, most people with DS have sufficient neuropathology for an AD diagnosis. Interestingly, atherosclerosis and hypertension are atypical in DS with age, suggesting the lack of thes...

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Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Head, Elizabeth, Phelan, Michael J., Doran, Eric, Kim, Ronald C., Poon, Wayne W., Schmitt, Frederick A., Lott, Ira T.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709935/
https://ncbi.nlm.nih.gov/pubmed/29195510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0499-4
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