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Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling

Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic...

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Foilsithe in:Korean J Physiol Pharmacol
Main Authors: Jiang, Tao, Wang, Xiu-qin, Ding, Chuan, Du, Xue-lian
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709474/
https://ncbi.nlm.nih.gov/pubmed/29200900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.6.579
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