Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling

Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic...

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Vydáno v:Korean J Physiol Pharmacol
Hlavní autoři: Jiang, Tao, Wang, Xiu-qin, Ding, Chuan, Du, Xue-lian
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709474/
https://ncbi.nlm.nih.gov/pubmed/29200900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.6.579
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