Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway

BACKGROUND: To investigate the neuroprotective effect of edaravone on excessive-dose propofol-induced neurotoxicity in the hippocampus of newborn rats and HT22 cells. METHODS: Cell proliferation was investigated by assessing ki67 expression in the neural stem of the hippocampus of newborn rats and b...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Yang, Yangliang, Yi, Jing, Pan, Mengzhi, Hu, Baoji, Duan, Hongwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020057/
https://ncbi.nlm.nih.gov/pubmed/33833500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S294557
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