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Induced Pluripotent Stem Cell-Derived Cardiomyocytes: A Platform for Testing For Drug Cardiotoxicity

Off-target cardiotoxicity has been a significant impediment to the development of new drugs. Traditional platforms for screening for cardiotoxicity are both overly sensitive and limited in their ability to predict cardiotoxicity that is often only uncovered after years of clinical use. A major imped...

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Pubblicato in:Prog Pediatr Cardiol
Autore principale: Bernstein, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708578/
https://ncbi.nlm.nih.gov/pubmed/29200805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ppedcard.2017.07.001
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