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Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium

Epoxide hydrolase (EH) enzymes catalyze the hydration of racemic epoxides to yield their corresponding vicinal diols. These enzymes present different enantio- and regioselectivity depending upon either the substrate structure or the substitution pattern of the epoxide ring. In this study, we computa...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Serrano-Hervás, Eila, Garcia-Borràs, Marc, Osuna, Sílvia
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708342/
https://ncbi.nlm.nih.gov/pubmed/29026902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob01847a
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