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Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium

Epoxide hydrolase (EH) enzymes catalyze the hydration of racemic epoxides to yield their corresponding vicinal diols. These enzymes present different enantio- and regioselectivity depending upon either the substrate structure or the substitution pattern of the epoxide ring. In this study, we computa...

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Bibliographic Details
Published in:Org Biomol Chem
Main Authors: Serrano-Hervás, Eila, Garcia-Borràs, Marc, Osuna, Sílvia
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708342/
https://ncbi.nlm.nih.gov/pubmed/29026902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob01847a
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