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Desensitization and Tolerance of Mu Opioid Receptors on Pontine Kölliker-Fuse Neurons

Acute desensitization of mu opioid receptors is thought to be an initial step in the development of tolerance to opioids. Given the resistance of the respiratory system to develop tolerance, desensitization of neurons in the Kölliker-Fuse (KF), a key area in the respiratory circuit, was examined. Th...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Levitt, Erica S., Williams, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708089/
https://ncbi.nlm.nih.gov/pubmed/29097440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109603
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