Detection of Activated Parietal Epithelial Cells on the Glomerular Tuft Distinguishes Early Focal Segmental Glomerulosclerosis from Minimal Change Disease

In rodents, parietal epithelial cells (PECs) migrating onto the glomerular tuft participate in the formation of focal segmental glomerulosclerosis (FSGS) lesions. We investigated whether immunohistologic detection of PEC markers in the initial biopsies of human patients with first manifestation of i...

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Gepubliceerd in:Am J Pathol
Hoofdauteurs: Smeets, Bart, Stucker, Fabien, Wetzels, Jack, Brocheriou, Isabelle, Ronco, Pierre, Gröne, Hermann-Josef, D’Agati, Vivette, Fogo, Agnes B., van Kuppevelt, Toin H., Fischer, Hans-Peter, Boor, Peter, Floege, Jürgen, Ostendorf, Tammo, Moeller, Marcus J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707202/
https://ncbi.nlm.nih.gov/pubmed/25307344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.007
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