Parietal Epithelial Cells Participate in the Formation of Sclerotic Lesions in Focal Segmental Glomerulosclerosis

The pathogenesis of the development of sclerotic lesions in focal segmental glomerulosclerosis (FSGS) remains unknown. Here, we selectively tagged podocytes or parietal epithelial cells (PECs) to determine whether PECs contribute to sclerosis. In three distinct models of FSGS (5/6-nephrectomy + DOCA...

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Hauptverfasser: Smeets, Bart, Kuppe, Christoph, Sicking, Eva-Maria, Fuss, Astrid, Jirak, Peggy, van Kuppevelt, Toin H., Endlich, Karlhans, Wetzels, Jack F.M., Gröne, Hermann-Josef, Floege, Jürgen, Moeller, Marcus J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2011
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137574/
https://ncbi.nlm.nih.gov/pubmed/21719782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010090970
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