Parietal Epithelial Cells Participate in the Formation of Sclerotic Lesions in Focal Segmental Glomerulosclerosis

The pathogenesis of the development of sclerotic lesions in focal segmental glomerulosclerosis (FSGS) remains unknown. Here, we selectively tagged podocytes or parietal epithelial cells (PECs) to determine whether PECs contribute to sclerosis. In three distinct models of FSGS (5/6-nephrectomy + DOCA...

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Detalhes bibliográficos
Main Authors: Smeets, Bart, Kuppe, Christoph, Sicking, Eva-Maria, Fuss, Astrid, Jirak, Peggy, van Kuppevelt, Toin H., Endlich, Karlhans, Wetzels, Jack F.M., Gröne, Hermann-Josef, Floege, Jürgen, Moeller, Marcus J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137574/
https://ncbi.nlm.nih.gov/pubmed/21719782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010090970
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