Subtotal Ablation of Parietal Epithelial Cells Induces Crescent Formation

Parietal epithelial cells (PECs) of the renal glomerulus contribute to the formation of both cellular crescents in rapidly progressive GN and sclerotic lesions in FSGS. Subtotal transgenic ablation of podocytes induces FSGS but the effect of specific ablation of PECs is unknown. Here, we established...

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Detalhes bibliográficos
Main Authors: Sicking, Eva-Maria, Fuss, Astrid, Uhlig, Sandra, Jirak, Peggy, Dijkman, Henry, Wetzels, Jack, Engel, Daniel R., Urzynicok, Torsten, Heidenreich, Stefan, Kriz, Wilhelm, Kurts, Christian, Ostendorf, Tammo, Floege, Jürgen, Smeets, Bart, Moeller, Marcus J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312496/
https://ncbi.nlm.nih.gov/pubmed/22282596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050449
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