Detection of Activated Parietal Epithelial Cells on the Glomerular Tuft Distinguishes Early Focal Segmental Glomerulosclerosis from Minimal Change Disease

In rodents, parietal epithelial cells (PECs) migrating onto the glomerular tuft participate in the formation of focal segmental glomerulosclerosis (FSGS) lesions. We investigated whether immunohistologic detection of PEC markers in the initial biopsies of human patients with first manifestation of i...

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Vydáno v:Am J Pathol
Hlavní autoři: Smeets, Bart, Stucker, Fabien, Wetzels, Jack, Brocheriou, Isabelle, Ronco, Pierre, Gröne, Hermann-Josef, D’Agati, Vivette, Fogo, Agnes B., van Kuppevelt, Toin H., Fischer, Hans-Peter, Boor, Peter, Floege, Jürgen, Ostendorf, Tammo, Moeller, Marcus J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707202/
https://ncbi.nlm.nih.gov/pubmed/25307344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.007
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