Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

Unbiased, “nontargeted” metabolite profiling techniques hold considerable promise for biomarker and pathway discovery, in spite of the lack of successful applications to human disease. By integrating nontargeted metabolomics, genetics, and detailed human phenotyping, we identified dimethylguanidino...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: O’Sullivan, John F., Morningstar, Jordan E., Yang, Qiong, Zheng, Baohui, Gao, Yan, Jeanfavre, Sarah, Scott, Justin, Fernandez, Celine, Zheng, Hui, O’Connor, Sean, Cohen, Paul, Vasan, Ramachandran S., Long, Michelle T., Wilson, James G., Melander, Olle, Wang, Thomas J., Fox, Caroline, Peterson, Randall T., Clish, Clary B., Corey, Kathleen E., Gerszten, Robert E.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707166/
https://ncbi.nlm.nih.gov/pubmed/29083323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95995
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