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Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

Unbiased, “nontargeted” metabolite profiling techniques hold considerable promise for biomarker and pathway discovery, in spite of the lack of successful applications to human disease. By integrating nontargeted metabolomics, genetics, and detailed human phenotyping, we identified dimethylguanidino...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: O’Sullivan, John F., Morningstar, Jordan E., Yang, Qiong, Zheng, Baohui, Gao, Yan, Jeanfavre, Sarah, Scott, Justin, Fernandez, Celine, Zheng, Hui, O’Connor, Sean, Cohen, Paul, Vasan, Ramachandran S., Long, Michelle T., Wilson, James G., Melander, Olle, Wang, Thomas J., Fox, Caroline, Peterson, Randall T., Clish, Clary B., Corey, Kathleen E., Gerszten, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707166/
https://ncbi.nlm.nih.gov/pubmed/29083323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95995
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