Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

Unbiased, “nontargeted” metabolite profiling techniques hold considerable promise for biomarker and pathway discovery, in spite of the lack of successful applications to human disease. By integrating nontargeted metabolomics, genetics, and detailed human phenotyping, we identified dimethylguanidino...

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Pubblicato in:J Clin Invest
Autori principali: O’Sullivan, John F., Morningstar, Jordan E., Yang, Qiong, Zheng, Baohui, Gao, Yan, Jeanfavre, Sarah, Scott, Justin, Fernandez, Celine, Zheng, Hui, O’Connor, Sean, Cohen, Paul, Vasan, Ramachandran S., Long, Michelle T., Wilson, James G., Melander, Olle, Wang, Thomas J., Fox, Caroline, Peterson, Randall T., Clish, Clary B., Corey, Kathleen E., Gerszten, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707166/
https://ncbi.nlm.nih.gov/pubmed/29083323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95995
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