Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells

Mycobacterium tuberculosis (Mtb) defends itself against host immunity and chemotherapy at several levels, including the repair or degradation of irreversibly oxidized proteins (IOPs). To investigate how Mtb deals with IOPs that can neither be repaired nor degraded, we used new chemical and biochemic...

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Publicat a:Cell Host Microbe
Autors principals: Vaubourgeix, Julien, Lin, Gang, Dhar, Neeraj, Chenouard, Nicolas, Jiang, Xiuju, Botella, Helene, Lupoli, Tania, Mariani, Olivia, Yang, Guangli, Ouerfelli, Ouathek, Unser, Michael, Schnappinger, Dirk, McKinney, John, Nathan, Carl
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707119/
https://ncbi.nlm.nih.gov/pubmed/25620549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.12.008
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