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Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin

Despite its central role in protein degradation little is known about the molecular mechanisms that sense, maintain, and regulate steady state concentration of ubiquitin in the cell. Here, we describe a novel mechanism for regulation of ubiquitin homeostasis that is mediated by phosphorylation of ub...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Lee, Sora, Tumolo, Jessica M, Ehlinger, Aaron C, Jernigan, Kristin K, Qualls-Histed, Susan J, Hsu, Pi-Chiang, McDonald, W Hayes, Chazin, Walter J, MacGurn, Jason A
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706963/
https://ncbi.nlm.nih.gov/pubmed/29130884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29176
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