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Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin

Despite its central role in protein degradation little is known about the molecular mechanisms that sense, maintain, and regulate steady state concentration of ubiquitin in the cell. Here, we describe a novel mechanism for regulation of ubiquitin homeostasis that is mediated by phosphorylation of ub...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lee, Sora, Tumolo, Jessica M, Ehlinger, Aaron C, Jernigan, Kristin K, Qualls-Histed, Susan J, Hsu, Pi-Chiang, McDonald, W Hayes, Chazin, Walter J, MacGurn, Jason A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706963/
https://ncbi.nlm.nih.gov/pubmed/29130884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29176
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