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Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin

Despite its central role in protein degradation little is known about the molecular mechanisms that sense, maintain, and regulate steady state concentration of ubiquitin in the cell. Here, we describe a novel mechanism for regulation of ubiquitin homeostasis that is mediated by phosphorylation of ub...

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發表在:eLife
Main Authors: Lee, Sora, Tumolo, Jessica M, Ehlinger, Aaron C, Jernigan, Kristin K, Qualls-Histed, Susan J, Hsu, Pi-Chiang, McDonald, W Hayes, Chazin, Walter J, MacGurn, Jason A
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706963/
https://ncbi.nlm.nih.gov/pubmed/29130884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29176
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