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A role for p53 in telomere protection

Telomeres cap the ends of chromosomes and are crucial for genome stability. The p53 protein (TP53) is a vital tumor suppressor, activating the transcription of numerous genes in response to cell stress. We reported that direct binding of p53 at human subtelomeres corresponds with local transcription...

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Dades bibliogràfiques
Publicat a:Mol Cell Oncol
Autors principals: Tutton, Stephen, Lieberman, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706955/
https://ncbi.nlm.nih.gov/pubmed/29209637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1143078
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