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Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection

Tumor suppressor protein 53 (p53) plays a central role in the control of genome stability, acting primarily through the transcriptional activation of stress-response genes. However, many p53 binding sites are located at genomic locations with no obvious regulatory-link to known stress-response genes...

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Detalhes bibliográficos
Publicado no:Bioessays
Autor principal: Lieberman, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157200/
https://ncbi.nlm.nih.gov/pubmed/27539745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600078
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