Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome (LQTS), which is caused by perturbation of ion channel function, and can lead to fainting, malig...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Dev
Autori principali: Duncan, Gary, Firth, Karl, George, Vinoj, Hoang, Minh Duc, Staniforth, Andrew, Smith, Godfrey, Denning, Chris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706629/
https://ncbi.nlm.nih.gov/pubmed/28992755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0172
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