Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome (LQTS), which is caused by perturbation of ion channel function, and can lead to fainting, malig...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cells Dev
Prif Awduron: Duncan, Gary, Firth, Karl, George, Vinoj, Hoang, Minh Duc, Staniforth, Andrew, Smith, Godfrey, Denning, Chris
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Original Research Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706629/
https://ncbi.nlm.nih.gov/pubmed/28992755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0172
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