Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome (LQTS), which is caused by perturbation of ion channel function, and can lead to fainting, malig...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Duncan, Gary, Firth, Karl, George, Vinoj, Hoang, Minh Duc, Staniforth, Andrew, Smith, Godfrey, Denning, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706629/
https://ncbi.nlm.nih.gov/pubmed/28992755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0172
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