CD19 regulates ADAM28‐mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells

As the first line of defence, marginal zone (MZ) B cells play principal roles in clearing blood‐borne pathogens during infection and are over‐primed in autoimmune diseases. However, the basic mechanisms underlying MZ B‐cell development are still unclear. We found here that CD19 deficiency blocked th...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Zhang, Yu, Zhu, Gaizhi, Xiao, He, Liu, Xiaoling, Han, Gencheng, Chen, Guojiang, Hou, Chunmei, Shen, Beifen, Li, Yan, Ma, Ning, Wang, Renxi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706524/
https://ncbi.nlm.nih.gov/pubmed/28707394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13276
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