Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP‐9 expression but not direct TJ proteins expression regulation

Blood‐spinal cord barrier (BSCB) disruption is a major process for the secondary injury of spinal cord injury (SCI) and is considered to be a therapeutic target for SCI. Previously, we demonstrated that metformin could improve functional recovery after SCI; however, the effect of metformin on BSCB i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Zhang, Di, Tang, Qian, Zheng, Gang, Wang, Chenggui, Zhou, Yifei, Wu, Yaosen, Xuan, Jun, Tian, Naifeng, Wang, Xiangyang, Wu, Yan, Xu, Huazi, Zhang, Xiaolei
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706495/
https://ncbi.nlm.nih.gov/pubmed/28699677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13235
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