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Host-guest interaction of β-cyclodextrin with isomeric ursolic acid and oleanolic acid: physicochemical characterization and molecular modeling study

Ursolic acid (UA) and oleanolic acid (OA) are insoluble drugs. The objective of this study was to encapsulate them into β-cyclodextrin (β-CD) and compare the solubility and intermolecular force of β-CD with the two isomeric triterpenic acids. The host-guest interaction was explored in liquid and sol...

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Détails bibliographiques
Publié dans:J Biomed Res
Auteurs principaux: Huang, Yuan, Quan, Peng, Wang, Yongwei, Zhang, Dongsheng, Zhang, Mingwan, Li, Rui, Jiang, Nan
Format: Artigo
Langue:Inglês
Publié: Editorial Department of Journal of Biomedical Research 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706432/
https://ncbi.nlm.nih.gov/pubmed/28958995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160073
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