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The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse

Opioids are currently the primary treatment method used to manage both acute and chronic pain. In the past two to three decades, there has been a surge in the use, abuse and misuse of opioids. The mechanism by which opioids relieve pain and induce euphoria is dependent on the drug crossing the blood...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Schaefer, Charles P., Tome, Margaret E., Davis, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706290/
https://ncbi.nlm.nih.gov/pubmed/29183383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0080-3
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