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The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse

Opioids are currently the primary treatment method used to manage both acute and chronic pain. In the past two to three decades, there has been a surge in the use, abuse and misuse of opioids. The mechanism by which opioids relieve pain and induce euphoria is dependent on the drug crossing the blood...

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Pubblicato in:Fluids Barriers CNS
Autori principali: Schaefer, Charles P., Tome, Margaret E., Davis, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706290/
https://ncbi.nlm.nih.gov/pubmed/29183383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0080-3
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