miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness

Rationale: Chemoresistance and subsequent recurrence of human urothelial bladder cancer (UBC) is partially driven by a subpopulation of tumor initiating cells, namely cancer stem cells (CSCs). However, the underlying molecular mechanism in chemotherapy-induced CSCs enrichment and following chemoresi...

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Publicado en:Theranostics
Autores principales: Zhang, Qing, Zhuang, Junlong, Deng, Yongming, Yang, Lin, Cao, Wenmin, Chen, Wei, Lin, Tingsheng, Lv, Xiaoyu, Yu, Hang, Xue, Yanshi, Guo, Hongqian
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706099/
https://ncbi.nlm.nih.gov/pubmed/29187903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21713
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