Blocking PGE(2)-induced tumour repopulation abrogates bladder cancer chemoresistance

Cytotoxic chemotherapy is effective in debulking tumour masses initially; however, in some patients tumours become progressively unresponsive after multiple treatment cycles. Previous studies have demonstrated that cancer stem cells (CSCs) are selectively enriched after chemotherapy through enhanced...

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Bibliographic Details
Published in:	Nature
Main Authors:	Kurtova, Antonina V., Xiao, Jing, Mo, Qianxing, Pazhanisamy, Senthil, Krasnow, Ross, Lerner, Seth P., Chen, Fengju, Roh, Terrence T., Lay, Erica, Ho, Philip Levy, Chan, Keith Syson
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4465385/ https://ncbi.nlm.nih.gov/pubmed/25470039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14034
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Blocking PGE(2)-induced tumour repopulation abrogates bladder cancer chemoresistance

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