Blocking PGE(2)-induced tumour repopulation abrogates bladder cancer chemoresistance

Cytotoxic chemotherapy is effective in debulking tumour masses initially; however, in some patients tumours become progressively unresponsive after multiple treatment cycles. Previous studies have demonstrated that cancer stem cells (CSCs) are selectively enriched after chemotherapy through enhanced...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Kurtova, Antonina V., Xiao, Jing, Mo, Qianxing, Pazhanisamy, Senthil, Krasnow, Ross, Lerner, Seth P., Chen, Fengju, Roh, Terrence T., Lay, Erica, Ho, Philip Levy, Chan, Keith Syson
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465385/
https://ncbi.nlm.nih.gov/pubmed/25470039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14034
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