Mutational Landscape of cfDNA Identifies Distinct Molecular Features Associated With Therapeutic Response to First-Line Platinum-Based Doublet Chemotherapy in Patients with Advanced NSCLC

Rationale To investigate whether the mutational landscape of circulating cell-free DNA (cfDNA) could predict and dynamically monitor the response to first-line platinum-based chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC). Methods Eligible patients were included and blood...

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Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Jiang, Tao, Li, Xuefei, Wang, Jianfei, Su, Chunxia, Han, Wenbo, Zhao, Chao, Wu, Fengying, Gao, Guanghui, Li, Wei, Chen, Xiaoxia, Li, Jiayu, Zhou, Fei, Zhao, Jing, Cai, Weijing, Zhang, Henghui, Du, Bo, Zhang, Jun, Ren, Shengxiang, Zhou, Caicun, Yu, Hui, Hirsch, Fred R.
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706097/
https://ncbi.nlm.nih.gov/pubmed/29187901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21687
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