Exosomes transmit T790M mutation‐induced resistance in EGFR‐mutant NSCLC by activating PI3K/AKT signalling pathway

Emerging evidence has shown that exosomes derived from drug‐resistant tumour cells are able to horizontally transmit drug‐resistant phenotype to sensitive cells. However, whether exosomes shed by EGFR T790M‐mutant–resistant NSCLC cells could transfer drug resistance to sensitive cells has not been i...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Liu, Xiaozhen, Jiang, Tao, Li, Xuefei, Zhao, Chao, Li, Jiayu, Zhou, Fei, Zhang, Limin, Zhao, Sha, Jia, Yijun, Shi, Jinpeng, Gao, Guanghui, Li, Wei, Zhao, Jing, Chen, Xiaoxia, Su, Chunxia, Ren, Shengxiang, Zhou, Caicun
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991626/
https://ncbi.nlm.nih.gov/pubmed/31894895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14838
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