Exosomes transmit T790M mutation‐induced resistance in EGFR‐mutant NSCLC by activating PI3K/AKT signalling pathway

Emerging evidence has shown that exosomes derived from drug‐resistant tumour cells are able to horizontally transmit drug‐resistant phenotype to sensitive cells. However, whether exosomes shed by EGFR T790M‐mutant–resistant NSCLC cells could transfer drug resistance to sensitive cells has not been i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Liu, Xiaozhen, Jiang, Tao, Li, Xuefei, Zhao, Chao, Li, Jiayu, Zhou, Fei, Zhang, Limin, Zhao, Sha, Jia, Yijun, Shi, Jinpeng, Gao, Guanghui, Li, Wei, Zhao, Jing, Chen, Xiaoxia, Su, Chunxia, Ren, Shengxiang, Zhou, Caicun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991626/
https://ncbi.nlm.nih.gov/pubmed/31894895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14838
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge