The Association between COX-2 Polymorphisms and Hematologic Toxicity in Patients with Advanced Non-Small-Cell Lung Cancer Treated with Platinum-Based Chemotherapy

BACKGROUND AND OBJECTIVE: Overexpression of COX-2 is proved to contribute to tumor promotion and carcinogenesis through stimulating cell proliferation, inhibiting apoptosis and enhancing the invasiveness of cancer cells. Apoptosis-related molecules are potential predictive markers for survival and t...

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Hauptverfasser: Zhou, Fei, Gao, Guanghui, Ren, Shengxiang, Li, Xuefei, He, Yayi, Zhou, Caicun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631232/
https://ncbi.nlm.nih.gov/pubmed/23620771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061585
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