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Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth by Inducing Mitotic Catastrophe

The current integrative pathobiological hypothesis states that pancreatic cancer (PDAC) develops and progresses in response to an interaction between known oncogenes and downstream epigenomic regulators. Congruently, this study tests a new combinatorial therapy based on the inhibition of the Aurora...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Mathison, Angela, Salmonson, Ann, Missfeldt, Mckenna, Bintz, Jennifer, Williams, Monique, Kossak, Sarah, Nair, Asha, de Assuncao, Thiago M., Christensen, Trace, Buttar, Navtej, Iovanna, Juan, Huebert, Robert, Lomberk, Gwen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705946/
https://ncbi.nlm.nih.gov/pubmed/28442587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0063
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