Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes

We have previously shown that amino acid changes in the human Kruppel-Like Factor (KLF) 11 protein is associated with the development of maturity onset diabetes of the young VII, whereas complete inactivation of this pathway by the −331 human insulin mutation causes neonatal diabetes mellitus. Here,...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Mathison, Angela, Escande, Carlos, Calvo, Ezequiel, Seo, Seungmae, White, Thomas, Salmonson, Ann, Faubion, William A., Buttar, Navtej, Iovanna, Juan, Lomberk, Gwen, Chini, Eduardo N., Urrutia, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588811/
https://ncbi.nlm.nih.gov/pubmed/26248217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1145
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