Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth by Inducing Mitotic Catastrophe

The current integrative pathobiological hypothesis states that pancreatic cancer (PDAC) develops and progresses in response to an interaction between known oncogenes and downstream epigenomic regulators. Congruently, this study tests a new combinatorial therapy based on the inhibition of the Aurora...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Mathison, Angela, Salmonson, Ann, Missfeldt, Mckenna, Bintz, Jennifer, Williams, Monique, Kossak, Sarah, Nair, Asha, de Assuncao, Thiago M., Christensen, Trace, Buttar, Navtej, Iovanna, Juan, Huebert, Robert, Lomberk, Gwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705946/
https://ncbi.nlm.nih.gov/pubmed/28442587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0063
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