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Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality
Epithelial injury has been proposed to be the initiating factor in the pathogenesis of idiopathic pulmonary fibrosis (IPF). We have shown previously that heparan sulfate 6-O-endosulfatase (Sulf) 2 is overexpressed in the hyperplastic type II alveolar epithelial cells (AECs) in the IPF lungs. By remo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Respir Cell Mol Biol |
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| Κύριος συγγραφέας: | |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Thoracic Society
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705905/ https://ncbi.nlm.nih.gov/pubmed/28657777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0367OC |
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