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Deficiency of the Purinergic Receptor 2X(7) Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the role of the purinergic receptor 2X(7) (PR2X(7))...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Oxid Med Cell Longev
Päätekijät: Blasetti Fantauzzi, Claudia, Menini, Stefano, Iacobini, Carla, Rossi, Chiara, Santini, Eleonora, Solini, Anna, Pugliese, Giuseppe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705892/
https://ncbi.nlm.nih.gov/pubmed/29270247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8962458
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