Wird geladen...

Deficiency of the Purinergic Receptor 2X(7) Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the role of the purinergic receptor 2X(7) (PR2X(7))...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Blasetti Fantauzzi, Claudia, Menini, Stefano, Iacobini, Carla, Rossi, Chiara, Santini, Eleonora, Solini, Anna, Pugliese, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705892/
https://ncbi.nlm.nih.gov/pubmed/29270247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8962458
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!