Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis

BACKGROUND: The onset of seropositive rheumatoid arthritis (RA) is preceded by the presence of specific autoantibodies in the absence of synovial inflammation. Only a subset of these at-risk individuals will develop clinical disease. This impedes efforts to implement early interventions that may pre...

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Bibliografske podrobnosti
izdano v:Ann Rheum Dis
Main Authors: Tak, Paul P, Doorenspleet, Marieke E, de Hair, Maria J H, Klarenbeek, Paul L, van Beers-Tas, Marian H, van Kampen, Antoine H C, van Schaardenburg, Dirkjan, Gerlag, Danielle M, Baas, Frank, de Vries, Niek
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2017
Teme:
Basic and Translational Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705849/
https://ncbi.nlm.nih.gov/pubmed/28790026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-211351
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