Discovery of invariant T cells by next generation sequencing of the human T cell receptor α chain repertoire

During infection and autoimmune disease, activation and expansion of T cells takes place. Consequently, the T cell receptor (TCR) repertoire contains information about ongoing and past diseases. Analysis and interpretation of the human TCR repertoire is hampered by its size and stochastic variation...

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Pubblicato in:J Immunol
Autori principali: van Schaik, Barbera, Klarenbeek, Paul, Doorenspleet, Marieke, van Kampen, Antoine, Moody, D. Branch, de Vries, Niek, Van Rhijn, Ildiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225161/
https://ncbi.nlm.nih.gov/pubmed/25339678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401380
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