Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) constitutes the most inherited kidney disease. Mutations in the PKD1 and PKD2 genes, encoding the polycystin 1 and polycystin 2 Ca(2+) ion channels, respectively, result in tubular epithelial cell-derived renal cysts. Recent clinical studies demon...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Ishimoto, Yu, Inagi, Reiko, Yoshihara, Daisuke, Kugita, Masanori, Nagao, Shizuko, Shimizu, Akira, Takeda, Norihiko, Wake, Masaki, Honda, Kenjiro, Zhou, Jing, Nangaku, Masaomi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705822/
https://ncbi.nlm.nih.gov/pubmed/28993480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00337-17
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