Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Human autosomal recessive polycystic kidney disease (ARPKD) produces kidneys which are massively enlarged due to multiple cysts, hypertension, and congenital hepatic fibrosis characterized by dilated bile ducts and portal hypertension. The PCK rat is an orthologous model of human ARPKD with numerous...

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Detalhes bibliográficos
Main Authors: Yoshihara, Daisuke, Kugita, Masanori, Sasaki, Mai, Horie, Shigeo, Nakanishi, Koichi, Abe, Takaaki, Aukema, Harold M., Yamaguchi, Tamio, Nagao, Shizuko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855683/
https://ncbi.nlm.nih.gov/pubmed/24324698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081480
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