Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) constitutes the most inherited kidney disease. Mutations in the PKD1 and PKD2 genes, encoding the polycystin 1 and polycystin 2 Ca(2+) ion channels, respectively, result in tubular epithelial cell-derived renal cysts. Recent clinical studies demon...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ishimoto, Yu, Inagi, Reiko, Yoshihara, Daisuke, Kugita, Masanori, Nagao, Shizuko, Shimizu, Akira, Takeda, Norihiko, Wake, Masaki, Honda, Kenjiro, Zhou, Jing, Nangaku, Masaomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705822/
https://ncbi.nlm.nih.gov/pubmed/28993480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00337-17
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